Immunall Data Sheet

Product Name: Immunall, patented at 4 November 1999

Patent number 1013497

Purpose: to improve general horse fitness, to help the immune system, and to balance internal organ systems for an optimal response to stress and inflammation.

Effectiveness: the product improves vitality by releasing extra energy and regulating catabolic functions. In addition, the immune system will be stimulated and the function of internal organs, whose purposes are closely related to natural defences against stress and microorganisms, will be harmonised. The product helps to enhance the recovery of damaged tissue by oedema re sorption and cellular protection.

The patented combination consists of alcoholic extracts of Allium sativum, Uncaria tomentosa, Eleuterococcus scenticosus, Echinacea purpurea, Juglans regia, Carduus marianus and Viola tricolor.

Desired physiological effects: When formulating Immunall equestrian supplements, it was recognized that physical health and immune functions are closely related to mental well-being. Therefore, immune-stimulating and body purifying herbs have been combined with the adaptogenic medicinal plant Eleuterococcus scenticosus.

1.Improvement of General Condition

• Energy provision and resistance to stress: Eleuterococcus contains Eleutherosides, which provide a significant strengthening and tonic impact. The physiological effects combine energy mobilization (primarily through intensified utilization of glucose) with a stress-protective effect. (facilitated by the change in regulation of the central nervous system (hypothalamic-hypophysis system) and hormonal (adrenal, prostaglandin) production.)

• Adjustment of the digestive system: Allium sativum eliminates intestinal spasms, adjusts peristalsis and enhances the activity of the gastrointestinal glands. Juglans regia contains tannins and naphtoquinone-derivates, which positively influence the recovery of the intestinal mucous membrane after infection.

• Cleansing: Sylimarin in Carduus marianus stimulates and protects liver cells in the process of detoxification of harmful metabolites. In addition, Carduus enhances the production of bile. Viola tricolor supports the kidneys in removing small molecular metabolic waste from the blood (dieresis).

2. Improvement of Resistance Against Infections in horse care

Immunall contains three herbs, Juglans, Echinacea and Uncaria, each of them combining inhibitory effects on the growth of micro-organisms with immune-stimulating properties.

• Anti-inflammatory activity: Echinacea purpurea (caffeic acids) and Juglans regia (naphtoquinone derivatives) have bactericide and fungicide properties. Glycosides from Uncaria tomentosa and Echinacea inhibit viral attack on tissue. In addition, Echinacea protects cells by preventing micro-organisms from attaching and multiplying.

• Stimulation and support of the immune system: Caffeic acids, polysaccharides and glycoproteins from Echinacea, polysaccharides from Eleuterococcus and quinovic acid glycosides and triterpenes from Uncaria enhance oral and/or cell-mediated defence mechanisms. Juglans stimulates the lymphatic system. Echinacea and Eleuterococcus regulate the stress induced production of prostaglandin’s (chemicals related to cell inflammation) and ACTH (a hormone produced in reaction to stress) ) to an effective and controllable degree. In this process Echinacea stimulates the production of ACTH, while Eleuterococcus reduces the need for activators because the herb stimulates cells to build up more resistance to harmful influences.

3. Accelerated recovery after illness

• Tissue purification, oedema re sorption: Echinacea increases phagocyte activity in removing local remnants of damaged tissue. In addition, Echinacea stimulates local activity of lymphatic vessels in transporting interstitial fluid. Viola tricolor purifies the blood by stimulating the diuretic process in the kidneys. Uncaria contributes to oedema re sorption by lowering the blood pressure.

• Tissue protection: Uncaria has anti-oxidant properties, making cells less susceptible to harmful stimuli (i.e. microbial toxins).

Storage: dry, cool, dark and sealed. During storage the extract fluid might show some precipitation of herbal material. Therefore it is advised to shake the fluid well before using it.

Shelf Life: 1.5 years

First-aid measures: Contact with eyes, flush with a lot of water. In case of swallowing large amounts, drink copious quantities of water.

Contra-indications: none known

Interactions with other drugs: none known

Toxicology: clinical data or medicinal experiences concerning harmful effects of overdoses are not reported.

Side effects: none known